Objective:

During the course in winter semester of students acquire knowledge about causes of pathological states, molecular, cellular, organ and systemic mechanisms of pathogenesis of major medical syndromes, symptoms, and diseases. Students study the basic clinical terminology, role of genetic and environmental factors in development of the diseases, general mechanisms of disease development. The course starts with studying the typical pathological processes: cell damage, inflammation, fever, disorders of nutrition macro- and microelements’ balance, water and acid-base balance. Later on students acquire knowledge about typical disorders in the blood system and haemostasis. Pathophysiology of digestive system and main neurologic disorders is also taught during the course.

During the course in summer semester of study students study common principles of the pathogenesis of the most important disorders of respiratory, cardiovascular, endocrine systems and kidneys, provided with interpretation of typical clinical case studies. Student learn to analyse role of different risk factors in pathogenesis of atherosclerosis, arterial hypertension, bronchial asthma, COPD, diabetes mellitus, kidney failure and other important medical states, comparing common and different pathways in pathogenesis of these states. Aetiology, pathogenesis and clinical manifestations of life-threatening states (shock, coma, heart/respiratory/kidney failures) are explained together with main principles of diagnostics, treatment and prophylaxis of the disorders. The students are taught to consider the complex relations between causes, dynamics and progress of diseases and to perceive the integrative essence of medicine.

Head teacher: Prof. MUDr. Martin Petřek

• Course distribution: 3rd year, 5th and 6th semester
• Lectures: 30 hours/semester
• Exercises: 45 hours in winter, 60 hours in summer
• Completed by: credit, examination
• Number of credits: 10

Actual study plans (syllabus) are published on the Moodle and on the website of the Faculty of Medicine.

Winter semester: The lectures are held in LLH – Left Lecture Hall. on Mondays, from 11:45 a.m. to 13:15 p.m.

Winter semester: The exercises are held in the seminar room of the Department of Pathophysiology on Wednesdays from 15.30 p.m. to 17.45 p.m. (group A) 

and on Thursday from 8.00 a.m. to 10.15 a.m. (group C); from 10.30 a.m. to 12.45 p.m. (group B).

Summer semester: The lectures are held in LLH – Left Lecture Hall. on Mondays, from 13:00 p.m. to 14:30 p.m.

Summer semester: The exercises are held in the seminar room of the Department of Pathophysiology on Wednesdays from 15.30 p.m. to 18.30 p.m. (group B) and on Thursdays, from 7.15 a.m. to 10.15 a.m. (group A); from 10.30 a.m. to 13.30 p.m. (group C).

Completed by: Credit; Examination

The conditions for granting the credit are always stated in the current syllabus and on the Moodle.

Exam:

The conditions for passing the exam are always stated in the current syllabus and on the Moodle. Topics for the exam from Pathological Physiology are available on the Moodle.