General Medicine


During the course in winter semester of students acquire knowledge about causes of pathological states, molecular, cellular, organ and systemic mechanisms of pathogenesis of major medical syndromes, symptoms, and diseases. Students study the basic clinical terminology, role of genetic and environmental factors in development of the diseases, general mechanisms of disease development. The course starts with studying the typical pathological processes: cell damage, inflammation, fever, disorders of nutrition macro- and microelements’ balance, water and acid-base balance. Later on students acquire knowledge about typical disorders in the blood system and haemostasis. Pathophysiology of digestive system and main neurologic disorders is also taught during the course.

During the course in summer semester of study students study common principles of the pathogenesis of the most important disorders of respiratory, cardiovascular, endocrine systems and kidneys, provided with interpretation of typical clinical case studies. Student learn to analyse role of different risk factors in pathogenesis of atherosclerosis, arterial hypertension, bronchial asthma, COPD, diabetes mellitus, kidney failure and other important medical states, comparing common and different pathways in pathogenesis of these states. Aetiology, pathogenesis and clinical manifestations of life-threatening states (shock, coma, heart/respiratory/kidney failures) are explained together with main principles of diagnostics, treatment and prophylaxis of the disorders. The students are taught to consider the complex relations between causes, dynamics and progress of diseases and to perceive the integrative essence of medicine.

Teachers: Prof. MUDr. Martin Petřek, CSc., Gabriella Cápec, Ph.D., Szergej Cápec, Ph.D.

  • Course distribution: 3rd year, 5th and 6th semester
  • Lectures: 30 hours/semester
  • Exercises: 45 hours in winter, 60 hours in summer
  • Completed by: credit, examination
  • Number of credits: 10

You can download study plans (syllabus): winter, summer.

Winter semester: The lectures are held in LLH – Left Lecture Hall. on Mondays, from 11:45 a.m. to 13:15 p.m.

Winter semester: The exercises are held in the seminar room of the Department of Pathophysiology on Thursday:

  • Group C – from 8:00 a.m. to 10:15 a.m.
  • Group B – from 10:30 a.m. to 12:45 p.m.
  • Group A – from 13:30 p.m. to 15:45 p.m.

Summer semester: The lectures are held in LLH – Left Lecture Hall. on Mondays, from 13:00 p.m. to 14:30 p.m.

Summer semester: The exercises are held in the seminar room of the Department of Pathophysiology on Wednesday:

  • Group B – from 13:45 p.m. to 16:45 p.m.

and Thursday:

  • Group A – from 7:15 a.m. to 10:15 a.m.
  • Group C – from 10:30 a.m. to 13:30 p.m.

Completed by: Credit; Examination

Credit conditions are as follows:

1) The participation of students in practical exercises (and the process of justification and substitutions of absences) is regulated according to the Directive of the dean of the faculty of medicine and dentistry LF-B-18/14 (article 7. item 1.). Substitutions are provided at the 15th week of the study.

2) Credit will be granted upon successful answering 2/3 of questions from the respective term topics in the final test on the computer in the 15th week of the term. To take (or re-take) the Credit final test students must register on STAG.

3) For students, who were active during the term and in all ongoing tests achieved average score over 2/3 of questions answered*, final test will not be mandatory.

4) There are two possibilities for correction of unsuccessful credit test; after that, at the discretion of the department, opportunity for oral correction with at least two teachers will be considered.

*bonification of up to 10% of average score can be earned by presenting a topic selected from department list.


The examination starts with the written part (20 questions on computer), then the oral part follows (2 questions, each from winter and summer term). The exam is passed when student is successful in both written and oral parts; minimum 60% of test questions must be answered.

You can download topics for the exam from pathological physiology here.