The major objective of the course in summer semester is to provide students of dentistry with knowledge that enables them to understand the causes of pathological states and the molecular, cellular, organ and systemic mechanisms of development of medical syndromes, symptoms, and major diseases. The course starts with studying the typical pathological processes: cell damage, inflammation, fever, disorders of water, ion and acid-base balance. Further on during the course students study pathophysiology of respiratory, cardiovascular system, blood and coagulation. Special attention is provided to manifestations of the systemic diseases in oral cavity, and role of the disorders of oral cavity in aetiology and pathogenesis of the systemic diseases.

During the course in winter semester dentistry students of acquire knowledge about molecular, cellular, organ and systemic mechanisms of pathogenesis of disorders of nutrition, gastrointestinal tract, kidneys, endocrine and nervous system. Pathophysiology of disorders of connective tissues and bones is also discussed. Students study systemic manifestations of abovementioned disorders and emphasis is made on pathogenesis of orofacial changes. Students learn to analyze typical clinical case studies related to dentistry praxis with reference to common principles of aetiology and pathogenesis of diseases.

Teachers: Prof. MUDr. Martin Petřek, CSc., Gabriella Cápec, Ph.D., Szergej Cápec, Ph.D.

  • Course distribution: 2nd and 3rd year, 4th and 5th semester
  • Lectures: 30 hours in 4th semester, 15 hours in 5th semester
  • Exercises: 45 hours/semester
  • Completed by: credit, examination
  • Number of credits: 8

You can download study plans (syllabus): summer (4th semester), winter (5th semester)

Summer semester

  • The LECTURES are held in the No.2.517 room at New Building on Monday from 8.00 to 9:30 a.m.
  • The EXERCISES are held in the No.2.517 room at New Building on Monday from 9.45 to 12.00 a.m.

Winter semester

  • The LECTURES are held in the RLH – Right Lecture Hall on Mondays, from 8.00 a.m. to 9.30 a.m. on even weeks of the year, starting from 38th week.
  • The EXERCISES are held in the RLH – Right Lecture Hall on Mondays, from 9.45 a.m., to 11. 15 a.m. on even weeks and from 8.00 to 11.15 on odd weeks of the year.

Completed by: Credit. Examination.

Credit conditions are as follows:

1) The participation of students in practical exercises (and the process of justification and substitutions of absences) is regulated according to the Directive of the dean of the faculty of medicine and dentistry LF-B-18/14 (article 7. item 1.). Substitutions are provided at the 15th week of the study.

2) Credit will be granted upon successful answering 2/3 of questions from the respective term topics in the final test on the computer in the 15th week of the term. To take (or re-take) the Credit final test students must register on STAG.

3) For students, who were active during the term and in all ongoing tests achieved average score over 2/3 of questions answered*, final test will not be mandatory.

4) There are two possibilities for correction of unsuccessful credit test; after that, at the discretion of the department, opportunity for oral correction with at least two teachers will be considered.

*bonification of up to 10% of average score can be earned by presenting a topic selected from department list.


The examination starts with the written part (20 questions on computer), then the oral part follows (2 questions, each from winter and summer term). The exam is passed when student is successful in both written and oral parts; minimum 60% of test questions must be answered.

You can download topics for the exam from pathological physiology here.